蛋白名称
Eomesodermin homolog
免疫原
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
特异性
EOMES Monoclonal Antibody detects endogenous levels of EOMES protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
EOMES; TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
背景
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
功能
similarity:Contains 1 T-box DNA-binding domain.,
