蛋白名称
Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (hEAG2) (Voltage-gated potassium channel subunit Kv10.2)
免疫原
Synthetic Peptide of Kv10.2 AA range: 264-314
特异性
Kv10.2 protein(A260) detects endogenous levels of Kv10.2
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using specific immunogen.
其他名称
Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2;hEAG2;Voltage-gated potassium channel subunit Kv10.2)
背景
This gene encodes a member of voltage-gated potassium channels. Members of this family have diverse functions, including regulating neurotransmitter and hormone release, cardiac function, and cell volume. This protein is an outward-rectifying, noninactivating channel. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
功能
alternative products:Experimental confirmation may be lacking for some isoforms,domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly.,sequence caution:Translated as Gly.,similarity:Belongs to the potassium channel family. H (Eag) subfamily.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 1 PAS (PER-ARNT-SIM) domain.,subunit:The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH1/EAG.,tiss
