反应种属
Human;Rat;Mouse;;Cat
蛋白名称
Guanine nucleotide-binding protein-like 3-like protein
免疫原
The antiserum was produced against synthesized peptide derived from human GNL3L. AA range:71-120
特异性
GNL3L Monoclonal Antibody detects endogenous levels of GNL3L protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
GNL3L; Guanine nucleotide-binding protein-like 3-like protein
背景
The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],
功能
domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family.,