蛋白名称
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
免疫原
The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50
特异性
BRAF35 Monoclonal Antibody detects endogenous levels of BRAF35 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
HMG20B; BRAF35; HMGX2; HMGXB2; SMARCE1R; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SMARCE1-related protein; BRCA2-associated factor 35; HMG box-containing protein 20B; HMG domain-
背景
function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 HMG box DNA-binding domain.,subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2.,subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.,tissue specificity:Ubiquitously expressed in adult tissues.,
功能
function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 HMG box DNA-binding domain.,subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2.,subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.,tissue specificity:Ubiquitously expressed in adult tissues.,
