基因名称(Gene Name)
ST8SIA1 SIAT8 SIAT8A
蛋白名称
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialytransferase St8Sia I) (ST8SiaI)
免疫原
Synthesized peptide derived from human ST8SIA1. AA range:36-136
特异性
This antibody detects endogenous levels of ST8SIA1 at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
ST8SIA1 SIAT8 SIAT8A;Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (Ganglioside GT3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialytransferase St8Sia I) (ST8SiaI)
功能
Catalyzes the addition of sialic acid in alpha 2 ,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid . Can catalyze the addition of a second alpha-2 ,8-sialic acid to GD3 to form GT3 . Can use GM1b , GD1a and GT1b as acceptor substrates to synthesize GD1c , GT1a and GQ1b respectively . Can synthesize unusual tetra- and pentasialylated lactosylceramide derivatives identified as GQ3 (II3Neu5Ac4-Gg2Cer) and GP3 (II3Neu5Ac5-Gg2Cer) in breast cancer cells .
