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货号: YP-Ab-19593
促销价:

产品介绍

反应种属
Human,Mouse
应用范围
WB
抗体类型
多克隆抗体
基因名称(Gene Name)
ATAD2 L16 PRO2000
蛋白名称
ATPase family AAA domain-containing protein 2 (AAA nuclear coregulator cancer-associated protein) (ANCCA)
分子量(DA)
159kD
免疫原
Synthesized peptide derived from human ATAD2. AA range:228-328
特异性
This antibody detects endogenous levels of ATAD2 at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB 1:500-2000
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
ATAD2 L16 PRO2000;ATPase family AAA domain-containing protein 2 (AAA nuclear coregulator cancer-associated protein) (ANCCA)
背景
功能
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes , such as CCND1 , MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

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