蛋白名称
Potential tRNA (adenine (58) -N (1) ) -methyltransferase catalytic subunit TRMT61B (EC 2.1.1.220)
免疫原
Synthesized peptide derived from human TRMT61B. AA range:51-151
特异性
This antibody detects endogenous levels of TRMT61B at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
TRMT61B;Potential tRNA (adenine (58) -N (1) ) -methyltransferase catalytic subunit TRMT61B (EC 2.1.1.220)
功能
Methyltransferase that catalyzes the formation of N (1) -methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion , including tRNA (Leu) (deciphering codons UUA or UUG) , tRNA (Lys) and tRNA (Ser) (deciphering codons UCA , UCU , UCG or UCC) . Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function . In addition to tRNA N (1) -methyltransferase activity , also acts as a mRNA N (1) -methyltransferase by mediating methylation of adenosine residues at the N (1) position of MT-ND5 mRNA , leading to interfere with mitochondrial translation .
