蛋白名称
Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Shingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short]
免疫原
Synthesized peptide derived from human GM2A. AA range:1-31
特异性
This antibody detects endogenous levels of GM2A at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
GM2A;Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Shingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short]
功能
The large binding pocket can accommodate several single chain phospholipids and fatty acids , GM2A also exhibits some calcium-independent phospholipase activity (By similarity) . Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3 (By similarity) . Has cholesterol transfer activity .
