蛋白名称
Early growth response protein 1/2
免疫原
The antiserum was produced against synthesized peptide derived from human EGR1/2. AA range:371-420
特异性
Egr1/2 Polyclonal Antibody detects endogenous levels of Egr1/2 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
其他名称
EGR1/2;Early growth response protein 1/2;EGR1 ;
KROX24 ;
ZNF225 ;
Early growth response protein 1 ;
EGR-1 ;
AT225 ;
Nerve growth factor-induced protein A ;
NGFI-A ;
Transcription factor ETR103 ;
Transcription factor Zif268 ;
Zinc finger protein 225 ;
Zinc finger protein Krox-24 ;
EGR2 ;
KROX20
背景
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq , Dec 2014] ,
功能
Function:Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site) . Activates the transcription of target genes whose products are required for mitogenesis and differentiation. ,induction:By growth factors. ,similarity:Belongs to the EGR C2H2-type zinc-finger protein family. ,similarity:Contains 3 C2H2-type zinc fingers. ,
