蛋白名称
Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Rotamase PPIL2)
免疫原
Synthesized peptide derived from human PPIL2. AA range:223-323
特异性
This antibody detects endogenous levels of PPIL2 at Human, Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation . May also function as a chaperone , playing a role in transport to the cell membrane of BSG/Basigin for instance . Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity .
