分子量（DA）
Calculated MW: 20 kDa; Observed MW: 20 kDa
免疫原
Synthetic peptide of human IL7
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
背景
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
