分子量（DA）
Calculated MW: 84 kDa; Observed MW: 84 kDa
免疫原
A synthesized peptide derived from human NAK/TBK1 (N-term)
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
其他名称
TBK1; NAK; Serine/threonine-protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1
背景
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.
