分子量（DA）
Calculated MW: 36 kDa;Observed MW:39kDa
Clonality
免疫原
A synthesized peptide derived from human Phospho-IKB alpha (S36)
稀释比例
WB: 1/500-1/1000 FC: 1/50
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
其他名称
I kappa B alpha; IkappaBalpha; IkB-alpha; IKBA; IKBalpha; MAD3; NF kappa B inhibitor alpha; NFKBI; NFKBIA;
背景
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
