分子量(DA)
Calculated MW: 78 kDa; Observed MW: 78 kDa
免疫原
A synthetic peptide of human Apg7
储存
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
其他名称
hAGP7; Ubiquitin-activating enzyme E1-like protein; APG7L
背景
The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.