蛋白名称
Podocalyxin-like protein 2
免疫原
Synthesized peptide derived from the Internal region of human Endoglycan.
特异性
Endoglycan Polyclonal Antibody detects endogenous levels of Endoglycan protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
PODXL2; Podocalyxin-like protein 2; Endoglycan
背景
This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012],
功能
PTM:Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides.,PTM:Sulfation and sialylated O-linked oligosaccharides are necessary for SELL/L-selectin binding.,similarity:Belongs to the podocalyxin family.,subunit:Homodimer; disulfide-linked. Binds to SELL/L-selectin.,tissue specificity:Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.,
