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p19 Polyclonal Antibody

货号: YP-Ab-16761
促销价:

产品介绍

反应种属
Human;Rat;Mouse;
应用范围
IHC;IF;WB;ELISA
抗体类型
多克隆抗体
基因名称(Gene Name)
CDKN2D
蛋白名称
Cyclin-dependent kinase 4 inhibitor D
分子量(DA)
免疫原
The antiserum was produced against synthesized peptide derived from human CDKN2D. AA range:96-145
特异性
p19 Polyclonal Antibody detects endogenous levels of p19 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
CDKN2D; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d
背景
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008],
功能
function:Interacts strongly with CDK4 and CDK6 and inhibits them.,similarity:Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.,similarity:Contains 4 ANK repeats.,

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