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货号: YP-Ab-16731
促销价:

产品介绍

反应种属
Human;Mouse;Rat
应用范围
WB;IHC;IF;ELISA
抗体类型
多克隆抗体
基因名称(Gene Name)
CCNG1
蛋白名称
Cyclin-G1
分子量(DA)
29kD
免疫原
The antiserum was produced against synthesized peptide derived from human Cyclin G. AA range:161-210
特异性
Cyclin G Polyclonal Antibody detects endogenous levels of Cyclin G protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
CCNG1; CCNG; CYCG1; Cyclin-G1; Cyclin-G
背景
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
功能
developmental stage:Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.,function:May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.,induction:Activated in breast and prostate cancer cells. Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,subcellular location:DNA replication foci after DNA damage.,tissue specificity:High levels in skeletal muscle, ovary, kidney and colon.,

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优品生物的抗体,可以回收利用几次?

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注:我们将孵育完毕后剩余的抗体回收到离心管中置于4℃保存,效价高的抗体可至少保存1周,至少重复利用3次。

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优品生物抗体成分?

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