蛋白名称
Testis-specific serine/threonine-protein kinase 6
免疫原
Synthesized peptide derived from the Internal region of human TSSK 6.
特异性
TSSK 6 Polyclonal Antibody detects endogenous levels of TSSK 6 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
TSSK6; SSTK; FKSG82; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK-6; Testis-specific kinase 6; Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase
背景
This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.,
