蛋白名称
NK-tumor recognition protein
免疫原
The antiserum was produced against synthesized peptide derived from human NKTR. AA range:784-833
特异性
NK-TR Polyclonal Antibody detects endogenous levels of NK-TR protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
NKTR; NK-tumor recognition protein; NK-TR protein; Natural-killer cells cyclophilin-related protein
背景
This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:Component of a putative tumor-recognition complex. Involved in the function of NK cells.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcellular location:Attached to the membrane via its N-terminus.,
