蛋白名称
FK506-binding protein-like
免疫原
The antiserum was produced against synthesized peptide derived from human FKBPL. AA range:251-300
特异性
FKBPL Polyclonal Antibody detects endogenous levels of FKBPL protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
FKBPL; DIR1; NG7; FK506-binding protein-like; WAF-1/CIP1 stabilizing protein 39; WISp39
背景
The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008],
功能
function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 TPR repeats.,subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.,tissue specificity:Ubiquitously expressed with higher levels in testis.,
