蛋白名称
FAD-linked sulfhydryl oxidase ALR
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GFER. AA range:51-100
特异性
ALR Polyclonal Antibody detects endogenous levels of ALR protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
GFER; ALR; HERV1; HPO; FAD-linked sulfhydryl oxidase ALR; Augmenter of liver regeneration; hERV1; Hepatopoietin
背景
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008],
功能
catalytic activity:4 R'C(R)SH + O(2) = 2 R'C(R)S-S(R)CR' + 2 H(2)O.,cofactor:FAD.,function:FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.,similarity:Contains 1 ERV/ALR sulfhydryl oxidase domain.,subunit:Homodimer.,
