蛋白名称
Melanocortin receptor 5
免疫原
The antiserum was produced against synthesized peptide derived from human MC5R. AA range:271-320
特异性
MC5-R Polyclonal Antibody detects endogenous levels of MC5-R protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
MC5R; Melanocortin receptor 5; MC5-R; MC-2
背景
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010],
功能
function:Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in the brain but not in the melanoma cells.,
