基因名称(Gene Name)
DDR1 CAK EDDR1 NEP NTRK4 PTK3A RTK6 TRKE
蛋白名称
DDR1 (Phospho Tyr796)
免疫原
Synthesized peptide derived from human DDR1 (Phospho Tyr796)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat DDR1 (Phospho Tyr796)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
其他名称
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1;EC 2.7.10.1;CD167 antigen-like family member A;Cell adhesion kinase;Discoidin receptor tyrosine kinase;HGK2;Mammary carcinoma kinase 10;MCK-10;Protein-tyrosine kinase 3A;Protein-tyrosine kinase RTK-6;TRK E;Tyrosine kinase DDR;Tyrosine-protein kinase CAK;CD antigen CD167a)
背景
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates.,function:May be involved in cell-cell interactions and recognition.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.,
功能
regulation of cell growth, regulation of cell-matrix adhesion, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell adhesion, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, sensory organ development, female pregnancy, embryo implantation, negative regulation of cell proliferation, response to organic substance, regulation of cell-substrate adhesion, phosphorylation, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, biological adhesion, regulation of cell adhesion, mammary gland development, regulation of growth, regulation of cell proliferation, ear development, gland development, response to protein stimulus,
