免疫原
Synthetic Peptide of Mas1
特异性
The antibody detects endogenous Mas1 protein.
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
来源
Polyclonal, Rabbit,IgG
稀释比例
WB: 1:2000-5000 IHC: 1:200-500. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
MAS1; MAS; Proto-oncogene Mas
背景
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],
功能
caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,
