基因名称(Gene Name)
TPPP TPPP1
蛋白名称
TPPP (Phospho-Ser18)
免疫原
Synthesized peptide derived from human TPPP (Phospho-Ser18)
特异性
This antibody detects endogenous levels of TPPP (Phospho-Ser18) at Human, Mouse,Rat
组成
Liquid in PBS containing 50% glycerol, and 0.179% sodium azide.
来源
Polyclonal, Rabbit,IgG
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
其他名称
Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)
功能
function:Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,similarity:Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed.,
