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货号: YP-Ab-03168
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产品介绍

反应种属
Human;Mouse
应用范围
IHC;IF;ELISA
抗体类型
多克隆抗体
基因名称(Gene Name)
PALLD
蛋白名称
Palladin
分子量(DA)
150kD
免疫原
Synthesized peptide derived from Palladin . at AA range: 450-530
特异性
Palladin Polyclonal Antibody detects endogenous levels of Palladin protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
PALLD; KIAA0992; CGI-151; Palladin; SIH002; Sarcoma antigen NY-SAR-77
背景
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
功能
caution:Was wrongly assigned as myoneurin (Ref.2).,disease:Genetic variations in PALLD are associated with susceptibility to pancreatic cancer type 1 (PNCA1) [MIM:606856]. Expression is increased early in the development of pancreatic cancer: in normal-appearing whole tissue immediately adjacent to cancer, in the pre-cancer, and in both the familial and sporadic forms of the cancer.,disease:Genetic variations in PALLD may be associated with myocardial infarction.,function:Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monome

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