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货号: YP-Ab-02847
促销价:

产品介绍

反应种属
Human;Rat
应用范围
WB;ELISA
抗体类型
多克隆抗体
基因名称(Gene Name)
ALDH3A1
蛋白名称
Aldehyde dehydrogenase dimeric NADP-preferring
分子量(DA)
50kD
免疫原
The antiserum was produced against synthesized peptide derived from human ALDH3A1. AA range:236-285
特异性
ALDH3A1 Polyclonal Antibody detects endogenous levels of ALDH3A1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Polyclonal, Rabbit,IgG
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
ALDH3A1; ALDH3; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1
背景
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008],
功能
catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homodimer.,tissue specificity:High levels in stomach, esophagus and lung; low level in the liver and kidney.,

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