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hHR23b mouse mAb

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货号: YP-Ab-00098
促销价：

产品介绍

反应种属
Human;Mouse;Rat;Monkey;Hamster
应用范围
WB;ICC;IHC
抗体类型
单克隆抗体
基因名称(Gene Name)
hr23b
蛋白名称
分子量（DA）
58kD
免疫原
Purified recombinant human hHR23b protein fragments expressed in E.coli.
特异性
This antibody detects endogenous levels of hHR23b and does not cross-react with related proteins.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Monoclonal, Mouse
稀释比例
wb dilution 1:1000 icc dilution 1:100
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
hHR 23b;hHR23B;HR 23B;HR23B;mHR 23B;mHR23B;P58;RAD 23B;RAD23 (S. cerevisiae) homolog B; RAD23 homolog B (S. cerevisiae);RAD23 homolog B;RAD23 yeast homolog of B;RAD23B; RD23B_HUMAN;UV excision repair protein RAD23 homolog B;XP C repair complementing complex 58 kDa;XP C repair complementing complex 58 kDa protein;XP C repair complementing protein;XP-C repair-complementing complex 58 kDa protein;XPC repair complementing complex 58 kDa;XPC repair complementing complex 58 kDa protein;XPC repair complementing protein.
背景
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011],
功能
domain:The ubiquitin-like domain mediates interaction with MJD.,function:Plays a central role both in proteosomal degradation of misfolded proteins and DNA repair. Central component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in DNA excision repair by stabilizing XPC protein. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes.,similarity:Belongs to the RAD23 family.,similarity:Contains 1 STI1 domain.,similarity:Contains 1 ubiquitin-like domain.,similarity:Contains 2 UBA domains.,subunit:Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B (By similarity). Interacts with the 26S protea

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优品生物的抗体，可以回收利用几次？

首先，一般抗体不推荐客户回收利用，抗体使用之后缓冲体系已经发生改变，不同客户在回收抗体的保存条件上也会有差异，所以抗体回收使用效果无法保证。另外，优品生物也做过一批抗体回收验证测试，测试结果显示不同抗体可回收次数不同，一般效价越高的抗体，可重复使用的次数越多，客户可根据实验情况来确定。
注：我们将孵育完毕后剩余的抗体回收到离心管中置于4℃保存，效价高的抗体可至少保存1周，至少重复利用3次。

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优品生物作为国产抗体品牌的优势？

优品生物是国产品牌，通过聚焦抗体与酶核心技术，致力于打破国际技术的垄断，我们拥有包括兔多克隆抗体、小鼠单克隆抗体、兔单克隆抗体的生产研发平台，同时也有包括WB,IP在内的检测平台，我们对每一支自产的抗体进行了严格的检测。当然，我们部分直销地区也可以帮客户代购进口品牌的产品。同时也有抗体定制服务。优品生物l抗体优势：1，严自检，保质量；2产品多，指标全；3，价格低，货期短。

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优品生物抗体成分？

优品生物抗体成分在平时工作当中，常会有客户咨询我们的抗体用的什么buffer进行保存，一般来说，我们的buffer的成分是：PBS含0.03%的proclin300、0.05%牛血清白蛋白、50%甘油；也有一些是PBS含0.03%的proclin300，50%甘油。防腐剂 Proclin 300活性成分主要是2-甲基-4-异噻唑啉-3-酮（MCI）和5-氯-2-甲基-4-异噻唑啉-3-酮（CMCI）。ProClin生物灭活剂能够迅速穿透细胞膜，抑制对细胞呼吸至关重要的特定酶，因此一接触微生物有机体就会立即抑制细胞活性。ProClin的多个特定毒性位点可以防止微生物产生高水平的耐药性。

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